{"id":10402,"date":"2022-11-16T19:04:58","date_gmt":"2022-11-16T18:04:58","guid":{"rendered":"https:\/\/sfbd.fr\/?p=10402&preview=true&preview_id=10402"},"modified":"2022-11-17T11:09:47","modified_gmt":"2022-11-17T10:09:47","slug":"honorable-prize-2022-dr-charalampos-babis-galouzis","status":"publish","type":"post","link":"https:\/\/sfbd.fr\/en\/2022\/11\/16\/honorable-prize-2022-dr-charalampos-babis-galouzis\/","title":{"rendered":"Honorable prize 2022: Dr. Charalampos Babis Galouzis"},"content":{"rendered":"

[vc_row][vc_column][vc_column_text]<\/p>\n

\u2192 Prize 300 \u20ac<\/strong><\/h5>\n

The honorable prize for the 2022 SFBD Thesis Prize has been awarded Dr. Charalampos \u2018Babis\u2019 GALOUZIS (Marseille Developmental Biology Institute, Marseille, director Dr. Benjamin Prud\u2019homme) for his thesis entitled \u201cTrans-homolog interaction of yellow controls its sex-biased expression pattern in the wing of\u00a0Drosophila biarmipes<\/i>\u201d. His work was published in Current Opinion in Cell Biology<\/a> and Science<\/a>. <\/em><\/p>\n

\"\"The work of the winner:<\/h5>\n

During his thesis, Babis Galouzis studied the sex-specific regulation of the X-linked gene yellow<\/i>, which in\u00a0Drosophila biarmipes<\/i>, a species closely related to the better-known\u00a0Drosophila melanogaster<\/i>, is required for the formation of a pigmented spot only present on the wing of males.
Babis discovered that, contrary to the common-held belief, the sex-specific pattern of expression of\u00a0yellow\u00a0<\/i>in\u00a0D. biarmipes\u00a0<\/i>wing is not controlled by genes of the sex determination pathway, but by interallelic interaction, a regulatory mechanism known as transvection. The two\u00a0yellow\u00a0<\/i>alleles can physically and functionally interact in XX females, thus leading to the silencing of a particular enhancer responsible for the wing spot expression pattern, but not in XY males, thereby creating a male-biased expression pattern of\u00a0yellow<\/i>.\"\"
These results, described in a paper entitled \u2018Transvection regulates the sex-biased expression of a fly X-linked gene\u2019, published in\u00a0Science<\/i>, are exciting for two reasons. First, they reveal for the first time the role of transvection in the regulation of a\u00a0Drosophila<\/i>\u00a0gene under physiological conditions.\u00a0 Second, this is the first example of sex-specific gene regulation that is independent of the sex determination pathway. The jury chose to reward the exceptional quality of Babis\u2019 work with an accessit prize.<\/p>\n

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[vc_row][vc_column][vc_column_text] \u2192 Prize 300 \u20ac The honorable prize for the 2022 SFBD Thesis Prize has been awarded Dr. Charalampos \u2018Babis\u2019…<\/p>\n","protected":false},"author":6,"featured_media":10403,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96],"tags":[],"yoast_head":"\nHonorable prize 2022: Dr. Charalampos Babis Galouzis - SFBD<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sfbd.fr\/2022\/11\/16\/honorable-prize-2022-dr-charalampos-babis-galouzis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Honorable prize 2022: Dr. Charalampos Babis Galouzis - SFBD\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column][vc_column_text] \u2192 Prize 300 \u20ac The honorable prize for the 2022 SFBD Thesis Prize has been awarded Dr. Charalampos \u2018Babis\u2019…\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sfbd.fr\/2022\/11\/16\/honorable-prize-2022-dr-charalampos-babis-galouzis\/\" \/>\n<meta property=\"og:site_name\" content=\"SFBD\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-16T18:04:58+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-11-17T10:09:47+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/sfbd.fr\/wp-content\/uploads\/2022\/11\/Transformed14-08-2018_25kby_attPX_hemi_posteclosion_male0001-copie.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1170\" \/>\n\t<meta property=\"og:image:height\" content=\"622\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@sfbd_biodev\" \/>\n<meta name=\"twitter:site\" content=\"@sfbd_biodev\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"glenda comai\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Organization\",\"@id\":\"https:\/\/sfbd.fr\/en\/#organization\",\"name\":\"Soci\u00e9t\u00e9 Fran\u00e7aise de Biologie du D\u00e9veloppement\",\"url\":\"https:\/\/sfbd.fr\/en\/\",\"sameAs\":[\"https:\/\/twitter.com\/sfbd_biodev\"],\"logo\":{\"@type\":\"ImageObject\",\"@id\":\"https:\/\/sfbd.fr\/en\/#logo\",\"inLanguage\":\"en-US\",\"url\":\"https:\/\/sfbd.fr\/wp-content\/uploads\/2019\/11\/Favicon.jpg\",\"contentUrl\":\"https:\/\/sfbd.fr\/wp-content\/uploads\/2019\/11\/Favicon.jpg\",\"width\":1324,\"height\":1324,\"caption\":\"Soci\u00e9t\u00e9 Fran\u00e7aise de Biologie du D\u00e9veloppement\"},\"image\":{\"@id\":\"https:\/\/sfbd.fr\/en\/#logo\"}},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/sfbd.fr\/en\/#website\",\"url\":\"https:\/\/sfbd.fr\/en\/\",\"name\":\"Soci\u00e9t\u00e9 Fran\u00e7aise de Biologie du D\u00e9veloppement\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/sfbd.fr\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/sfbd.fr\/en\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"ImageObject\",\"@id\":\"https:\/\/sfbd.fr\/2022\/11\/16\/honorable-prize-2022-dr-charalampos-babis-galouzis\/#primaryimage\",\"inLanguage\":\"en-US\",\"url\":\"https:\/\/sfbd.fr\/wp-content\/uploads\/2022\/11\/Transformed14-08-2018_25kby_attPX_hemi_posteclosion_male0001-copie.jpg\",\"contentUrl\":\"https:\/\/sfbd.fr\/wp-content\/uploads\/2022\/11\/Transformed14-08-2018_25kby_attPX_hemi_posteclosion_male0001-copie.jpg\",\"width\":1170,\"height\":622,\"caption\":\"ImageJ=1.52p unit=inch\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/sfbd.fr\/2022\/11\/16\/honorable-prize-2022-dr-charalampos-babis-galouzis\/#webpage\",\"url\":\"https:\/\/sfbd.fr\/2022\/11\/16\/honorable-prize-2022-dr-charalampos-babis-galouzis\/\",\"name\":\"Honorable prize 2022: Dr. Charalampos Babis Galouzis - 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