Morphogenesis of macroalgae<\/a>“, Station Biologique (Roscoff) <\/span>
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Motivations<\/span><\/b><\/p>\nJe souhaite renouveler ma candidature au CA de la SFBD, suite \u00e0 un premier mandat effectu\u00e9 de 2019 \u00e0 2022. Je suis DR1 CNRS, j\u2019\u00e9tudie l\u2019embryogen\u00e8se des algues brunes, en particulier la mise en place des axes de croissance, le patterning des tissus et la mise en place des tissus tri-dimensionnels. J\u2019utilise des approches d\u2019imagerie quantitative et de mod\u00e9lisation m\u00e9canique.<\/span><\/p>\nBilan de mon premier mandat\u00a0:<\/span><\/b> En tant que v\u00e9g\u00e9taliste, de surcro\u00eet phycologue, je pense avoir compl\u00e9t\u00e9 la diversit\u00e9 du CA en apportant et en essayant de partager mes convictions et pratiques parfois diff\u00e9rents de ceux de mes coll\u00e8gues animalistes. En particulier, sensibilis\u00e9e par le manque de moyen et la sous-repr\u00e9sentativit\u00e9 de certaines th\u00e9matiques de recherche, je suis sensible \u00e0 la promotion d\u2019une int\u00e9gration la plus large possible, qui s\u2019appuie sur le socle de connaissances et comp\u00e9tences issues des mod\u00e8les classiques. Notamment aupr\u00e8s des doctorant.e.s., qui ont pu profiter d\u2019inscription gratuite au dernier \u201cshaping life meeting\u201d organis\u00e9 par l\u2019IBDM. En plus d\u2019avoir offert l\u2019opportunit\u00e9 de pr\u00e9senter leurs travaux \u00e0 certains doctorants, cette op\u00e9ration a r\u00e9sult\u00e9 en l\u2019ajout de nouveaux\/elles adh\u00e9rent.e.s \u00e0 la SFBD.<\/span><\/p>\nSuite \u00e0 une r\u00e9flexion avec mes coll\u00e8gues du CA Yoan Coudert et Aude Maugarny-Cal\u00e8s, et avec l\u2019accord du reste du CA, nous proposons actuellement aux adh\u00e9rents un nouvel outil soutenant la prise de risque en biologie du d\u00e9veloppement: les bourses \u201ctransition de carri\u00e8re\u201d. Ces bourses financent des missions individuelles visant \u00e0 faciliter une reconversion par l\u2019apprentissage de nouvelles techniques ou de nouveaux mod\u00e8les d\u2019\u00e9tudes. L\u2019objectif est \u00e0 la fois de soutenir les chercheurs en fin de th\u00e8se ou post-doctorants \u00e0 se lancer dans une nouvelle aventure, et \u00e0 catalyser l\u2019\u00e9mergence de nouvelles th\u00e9matiques de recherche dans ce domaine.<\/span><\/p>\nFinalement, je suis tr\u00e9sori\u00e8re adjointe, mais Marie-Ange Bonin, la tr\u00e9sori\u00e8re principale, assure jusqu\u2019\u00e0 pr\u00e9sent toutes les t\u00e2ches ingrates avec brio.<\/span><\/p>\nPourquoi un 2\u00e8me mandat?<\/span><\/b> J\u2019ai la conviction que la SFBD peut s\u2019impliquer davantage dans le soutien \u00e0 la recherche en biologie du d\u00e9veloppement par des actions concr\u00e8tes et inclusives. La biologie du d\u00e9veloppement, en particulier v\u00e9g\u00e9tale mais aussi animale, entame un tournant vers de nouveaux mod\u00e8les exp\u00e9rimentaux, avec un attrait particulier r\u00e9cent pour le milieu marin qui est un r\u00e9servoir de m\u00e9canismes de d\u00e9veloppement alternatifs. Je serai honor\u00e9e de pouvoir accompagner ces changements en tant que membre du CA de la SFBD, entre autre au moyen des outils de soutien \u00e0 la prise de risque et \u00e0 la formation technique que la SFBD peut d\u00e9ployer.<\/span><\/p>\n
\nClaudio COLLINET, CR CNRS, IBDM (Marseille)<\/span>
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As a CNRS researcher at the Institut de Biologie du De\u0301veloppement de Marseille (IBDM) since 2016, I am very happy to submit my candidature as a member of the SFBD Advisory Board.<\/p>\n
I grew up in Naples (Italy) where I did a Master in Medical Biotechnology at the University of Naples Federico II. During my studies I have soon been more fascinated by the biology of living cells rather than its applications to medicine. This led me to join the laboratory of Marino Zerial at the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) in Dresden (Germany) for my PhD where I studied the mechanisms of endocytosis and endocytic trafficking in mammalian cells. For my postdoc I got interested in bridging my knowledge as cell biologist to a context of development and I joined the group of Thomas Lecuit at the IBDM to study epithelial dynamics during morphogenesis, with a specific focus on the underlying cellular processes. After my recruitment at the CNRS in 2016 I have pursued my research at the interface between cell biology, development and biophysics. I\u2019m interested in understanding how dynamic patterns of cell and tissue level contractility control epithelial morphogenesis by integrating genetic, mechanical and geometrical information. For that I use the Drosophila embryo as a model system.<\/p>\n
Beyond the lab I am very much aware of our central role as researchers in the education of younger generations, as well as in the communication of our results amongst peers and to the general public. To that end, I actively participate to several science outreaching initiatives, such as Declics meetings in French high schools or the organization of journe\u0301es portes ouvertes for students in our laboratories. I\u2019m involved in the direction of students in the lab and I participate to the teaching of research activities at different levels. Last but not least, I have also participated to the organization of scientific conferences such as the French Drosophila Research Conference in 2018.<\/p>\n
After many years of research at the bench and within our institute in Marseille, I wish now to give my contribution to the wider community of developmental biologists in France and abroad by dedicating some of my time to the growth of the SFBD. I participate regularly to the SFBD annual meetings and I particularly appreciate the dynamism and the plurality of the SFBD community which gathers developmental biologists in France and beyond. I think that the many activities of the SFBD aiming at supporting the growth of young scientists and networking opportunities between younger and more senior scientists are extremely valuable actions for the community. During my mandate I wish to continue supporting such efforts. I also wish to increase the visibility of the SFBD in France and abroad by promoting more joint meetings between the SFBD and other European developmental biology societies. Finally, I wish to bring to this community my vision, passion and expertise as a cell biologist, with the hope to further reinforce the bridge between the very close disciplines of cell and developmental biology. My motto is \u201cTo understand Development we need to study the underlying cellular activities and those can only be understood in the wider context of Development\u201d.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Pascal DE SANTA BARBARA, PhyMedExp, Universit\u00e9 de Montpellier<\/strong><\/span><\/p>\n![\"\"](\"https:\/\/sfbd.fr\/wp-content\/uploads\/2022\/11\/Sans-titre.jpg\")
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Membre de la Soci\u00e9t\u00e9 Fran\u00e7aise de Biologie du D\u00e9veloppement depuis plus de 20 ans, j\u2019ai pu appr\u00e9cier la richesse et la diversit\u00e9 de cette communaut\u00e9 qui initialement m\u2019a aid\u00e9 \u00e0 d\u00e9velopper une recherche bas\u00e9e sur la biologie du d\u00e9veloppement \u00e0 mon retour des USA.<\/p>\n
Mon \u00e9quipe localis\u00e9e \u00e0 Montpellier s\u2019int\u00e9resse au d\u00e9veloppement du tube digestif en utilisant le mod\u00e8le aviaire afin de mieux comprendre les m\u00e9canismes responsables de pathologies digestives. Cette recherche translationnelle, combinant \u00e9tudes fondamentales et cliniques, nous a permis de montrer l\u2019int\u00e9r\u00eat d\u2019utiliser l\u2019embryon de poulet pour identifier les m\u00e9canismes d\u2019immaturit\u00e9 et la r\u00e9activation de processus d\u00e9veloppementaux dans plusieurs pathologies touchant la motricit\u00e9 digestive chez l\u2019enfant. Ces \u00e9tudes nous ont amen\u00e9s \u00e0 \u00eatre en contact avec les associations de patients et ainsi \u00e0 apprendre \u00e0 informer diff\u00e9rentes parties de la soci\u00e9t\u00e9 (patients, lyc\u00e9ens\u2026) \u00e0 l\u2019utilit\u00e9 de la biologie du d\u00e9veloppement. Ces actions de m\u00e9diation scientifique sont n\u00e9cessaires et de plus en plus utiles pour renforcer le lien entre chercheurs et l\u2019ensemble de la population. Pour l\u2019ensemble de ces raisons, je souhaite m\u2019impliquer dans la vie et le fonctionnement de la Soci\u00e9t\u00e9 Fran\u00e7aise de Biologie du D\u00e9veloppement en me portant candidat \u00e0 son Conseil d\u2019Administration.<\/p>\n
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M\u00e9lanie GRACIA, Chercheuse post-doctorante, Institut Curie (Paris)<\/strong><\/span><\/p>\n<\/div>\n![\"\"](\"https:\/\/sfbd.fr\/wp-content\/uploads\/2022\/11\/GRACIA_Me\u0301lanie-225x300.jpg\")
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My name is M\u00e9lanie Gracia and I am a 32 years-old post-doctoral researcher passionate about developmental biology. In order to contribute to our developmentalist community and increase the visibility of our field, I would like to enter the SFBD board.<\/strong><\/p>\nFrom the moment I discovered developmental biology during my bachelor in Toulouse, it became my main scientific interest. The idea that a whole individual originates from a single cell is truly fascinating, and trying to understand how this unique cell could give rise to drastically different organisms depending on cells behaviors was appealing.<\/p>\n
It\u2019s with this in mind that I looked for my first internship, and completely fell in love with developmental biology, leading me a few years later to a PhD in Magali Suzanne lab at the CBI of Toulouse. During my PhD, I studied the mechanical impact of Epithelial-to-Mesenchymal Transition (EMT) on tissue morphogenesis by dissecting the intracellular reorganizations occurring in the early stages of EMT in Drosophila melanogaster<\/em>. In 2020, I was honored to receive the SFBD thesis prize for this work, and with this the opportunity to present my work during the SFBD meeting \u201cFrom cell to embryo\u201d in front of an audience of developmental biology specialists.<\/p>\nAfter my PhD defense, I joined Yohanns Bellaiche lab at the Curie Institute in Paris, where I am currently working on understanding the interplay between tissue compaction and cellular behaviors, such as cell division or cell death, during the development of the dorsal thorax of the fruit fly. Recently, I participated to public outreach, by presenting development biology and model organisms during the \u201cF\u00eate de la Sciences\u201d. This interaction with families and children comforted me on the importance of developing outreach to increase the visibility of our discipline, and help people better understand the importance of studying developmental biology.<\/p>\n
As a young researcher who benefited from the support of the society through a PhD award, I think that the work of the SFBD is essential to build up our community. To this end, I would like to join the SFBD board to be actively involved in the life of the development biology community, to promote our discipline and help young researcher benefit from the SFBD support, as I had before.<\/p>\n
\nNicolas HAUPAIX, chercheur post-doctorant, IRCAN (Nice)<\/span><\/strong><\/p>\n![\"\"](\"https:\/\/sfbd.fr\/wp-content\/uploads\/2022\/11\/IMG20210726104859-225x300.jpg\")
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Je m’appelle Nicolas Haupaix. J’ai obtenu mon doctorat en 2014 a\u0300 l’Universite\u0301 de Nice Sophia Antipolis sous la direction de Hitoyoshi Yasuo. J’ai poursuivi mon travail en tant que postdoc au Colle\u0300ge de France dans le laboratoire de Marie Manceau et a\u0300 l’Institut Max Planck pour la recherche interdisciplinaire dans le de\u0301partement de Jochen Rink. Je suis actuellement postdoc dans l’e\u0301quipe d’Eric Ro\u0308ttinger a\u0300 l’Institut de recherche sur le cancer et le vieillissement (IRCAN) a\u0300 Nice depuis septembre 2022. Mon parcours acade\u0301mique est marque\u0301 par l’utilisation de nombreux mode\u0300les expe\u0301rimentaux verte\u0301bre\u0301s et inverte\u0301bre\u0301s tels que la drosophile, les ascidies, les cailles du Japon, les planaires et les ane\u0301mones mais aussi des mode\u0300les non conventionnels tels que les perdrix, les faisans, les ratites et les planaires terrestres. Bien que profonde\u0301ment fascine\u0301 par chacun de ces mode\u0300les, je n’en ple\u0301biscite aucun car mon attrait pour eux re\u0301side dans les diffe\u0301rences parfois massives, souvent subtiles, de leurs me\u0301canismes de de\u0301veloppementaux.<\/p>\n
Mon projet actuel s’inscrit parfaitement dans cette de\u0301marche puisque je cherche a\u0300 identifier l’origine embryonnaire des cancers pe\u0301diatriques du syste\u0300me nerveux chez l’ane\u0301mone Nematostella vectensis. Ce projet tire parti de la simplicite\u0301 du syste\u0300me nerveux des cnidaires, de leur remarquable capacite\u0301 de re\u0301ge\u0301ne\u0301ration et de l’origine ancestrale du cancer.<\/p>\n
Ma candidature est motive\u0301e par l’envie de m’investir dans la communaute\u0301 scientifique d’une autre manie\u0300re que mon activite\u0301 de recherche. En rejoignant le bureau de la SFBD, je souhaite m’impliquer dans les activite\u0301s existantes et promouvoir le dynamisme de la biologie du de\u0301veloppement en France aupre\u0300s des autorite\u0301s, du grand public et aussi des scientifiques eux- me\u0302mes :<\/p>\n
\n- – \u00a0Je suis particulie\u0300rement inte\u0301resse\u0301 par le de\u0301veloppement d’actions et de communication aupre\u0300s des jeunes scientifiques (doctorants et postdocs) qui he\u0301sitent a\u0300 s’impliquer dans la communaute\u0301 scientifique en dehors de la paillasse (par manque de temps, de le\u0301gitimite\u0301, d’autocensure…) ou qui ne savent pas comment le faire.<\/li>\n
- – \u00a0Je souhaite e\u0301galement m’impliquer dans l’organisation d’activite\u0301s de me\u0301diation scientifique aupre\u0300s du grand public afin de promouvoir la recherche fondamentale et l’immense atout qu’elle repre\u0301sente pour l’avenir de la nation.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n
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Jean-L\u00e9on Ma\u00eetre, Chef d’\u00e9quipe \u00e0 l’Institut Curie (Paris)<\/strong><\/span><\/p>\n<\/div>\n![\"\"](\"https:\/\/sfbd.fr\/wp-content\/uploads\/2022\/11\/JLM-283x300.jpg\")
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I am fascinated by how the shapes of living organisms emerge during embryonic development. Since 2016, I lead a research group, which focuses on the shape changes of the early mammalian embryo using live microscopy and biophysical approaches on mouse embryos, as well as to some extent in other mammalian species such as humans. We like to borrow concepts from soft matter physics and material sciences to describe embryos, as this is essential to understand how the embryo changes shape. This leads us to talk to scientists from very different backgrounds such as physicists, which is quite enriching. Recently, we also started working with medical doctors and we are happy to see how some of the concepts proposed by the lab could help improve the treatments of infertility.<\/p>\n
The reason I would like to get more involved with the developmental biology community is that, as John Wallingford (almost) wrote in a beautiful piece in 2019: \u201cIf you want to know what gets me out of bed in the morning, most days it really is<\/em>\u201d preimplantation development! After 15 years doing research in developmental biology, I have very much enjoyed benefiting from the various events that our community has organized. Since 6 years that I do research in France, my team and I have also directly benefitted from the actions of the SFBD. I am simply keen to contribute and help keep this community as interesting and friendly as it is. I would also like very much to contribute making this community as welcoming as possible for the foreigners who honor us by joining the French research community. We need the best scientists to join us, wherever they come from! Finally, I would like to help making developmental biology more popular to other biologists and to the public. Since I am in France, I have taken every possible opportunities to talk to the public and made sure to pass on my passion for embryos. I would be glad to help further promote this aspect within the SFBD as well.<\/p>\n <\/p>\n
\nMathilde PARIS, CR CNRS \u00e0 l’IGFL (Lyon)<\/strong><\/span><\/p>\n![\"\"](\"https:\/\/sfbd.fr\/wp-content\/uploads\/2022\/11\/Mathilde_Paris_IGFL-300x300.png\")
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Je m\u2019appelle Mathilde PARIS et je suis chercheure CNRS a\u0300 l\u2019IGFL (Lyon). Je fais acte de candidature pour le conseil d\u2019administration de la SFBD.<\/p>\n
Je m\u2019inte\u0301resse a\u0300 l\u2019e\u0301volution des formes chez les animaux. Je cherche notamment a\u0300 comprendre comment des changements dans la re\u0301gulation de l\u2019expression des ge\u0300nes influencent des changements aux cours du de\u0301veloppement embryonnaire, qui me\u0300nent in fine a\u0300 des innovations morphologiques.<\/p>\n
J\u2019ai soutenu ma the\u0300se dans l\u2019e\u0301quipe de Vincent Laudet fin 2008 au LBMC (ENS de Lyon), puis ai fait deux stages post-doctoraux a\u0300 UC Berkeley dans les e\u0301quipes de Mike Eisen puis Lior Pachter (USA) et ai obtenu mon poste de charge\u0301e de recherche CNRS dans l\u2019e\u0301quipe de Benjamin Prud\u2019homme a\u0300 l\u2019IBDM (Marseille) en 2014. J\u2019ai inte\u0301gre\u0301 l\u2019e\u0301quipe de Michalis Averof en 2018 a\u0300 l\u2019IGFL (ENS de Lyon), ou\u0300 je suis actuellement.<\/p>\n
Mes sujets de recherche ont toujours e\u0301te\u0301 lie\u0301s a\u0300 la re\u0301gulation ge\u0301ne\u0301tique du de\u0301veloppement, dans un cadre e\u0301volutif. J\u2019ai travaille\u0301 sur l\u2019e\u0301volution de la re\u0301gulation de la me\u0301tamorphose par les hormones thyroi\u0308diennes (notamment chez l\u2019amphioxus) au cours de ma the\u0300se, puis sur l\u2019e\u0301volution de la re\u0301gulation du de\u0301veloppement pre\u0301coce et de la pigmentation chez diffe\u0301rentes espe\u0300ces de Drosophiles. J\u2019e\u0301tudie actuellement la re\u0301ge\u0301ne\u0301ration chez le Crustace\u0301 mode\u0300le Parhyale hawaiensis. Nous avons re\u0301cemment montre\u0301 que chez cet animal la re\u0301ge\u0301ne\u0301ration permet de recre\u0301er des pattes indiscernables des pattes intactes, ce qui sugge\u0300re que les me\u0301canismes implique\u0301s au cours de la re\u0301ge\u0301ne\u0301ration pourraient e\u0302tre les me\u0302mes que ceux responsables de la formation des pattes au cours de l\u2019embryoge\u0301ne\u0300se. Ces re\u0301sultats sugge\u0300rent que le re\u0301seau de re\u0301gulation de l\u2019embryoge\u0301ne\u0300se a e\u0301te\u0301 co-opte\u0301 au cours de l\u2019e\u0301volution. Cependant nous avons montre\u0301 que les me\u0302mes ge\u0300nes sont exprime\u0301s au cours de ces deux processi mais avec des dynamiques diffe\u0301rentes. Nous sommes en train de comparer les re\u0301seaux re\u0301gulatoires du de\u0301veloppement et de la re\u0301ge\u0301ne\u0301ration afin de comprendre comment ils peuvent mener a\u0300 la formation de membres identiques.<\/p>\n
J\u2019utilise des me\u0301thodes de ge\u0301nomique fonctionnelle (principalement RNA-seq et ATAC-seq, en \u00ab bulk \u00bb ou a\u0300 l\u2019e\u0301chelle de la cellule individuelle). J\u2019ai un profil interdisciplinaire, en biologie du de\u0301veloppement, en biologie mole\u0301culaire et e\u0301volutive et en bio-informatique et mode\u0301lisation (par exemple j\u2019ai re\u0301cemment de\u0301veloppe\u0301 un mode\u0300le baye\u0301sien pour e\u0301tudier l\u2019expression ge\u0301nique au cours de l\u2019embryoge\u0301ne\u0300se et de la re\u0301ge\u0301ne\u0301ration).<\/p>\n
Les raisons de ma candidature au conseil d\u2019administration de la SFBD sont les suivantes : – Je souhaite participer plus activement a\u0300 l\u2019organisation collective de la recherche franc\u0327aise.
\n– J\u2019avais e\u0301te\u0301 honore\u0301e de be\u0301ne\u0301ficier d\u2019une bourse SFBD pendant ma the\u0300se et je souhaite contribuer a\u0300 aider les nouveaux e\u0301tudiants a\u0300 profiter de ces bourses.
\n– J\u2019espe\u0300re que mes compe\u0301tences en ge\u0301nomique pourront e\u0302tre un comple\u0301ment utile au conseil d\u2019administration.<\/p>\n
En espe\u0301rant que ma candidature sera e\u0301value\u0301e positivement, veuillez agre\u0301er l\u2019expression de mes since\u0300res salutations.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Eric Theveneau, CR CNRS, CBI (Toulouse)<\/strong><\/span><\/p>\n<\/div>\n\n
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Biologiste du de\u0301veloppement de formation, je m\u2019inte\u0301resse principalement a\u0300 la fac\u0327on dont les cellules se de\u0301placent. Au cours des 20 dernie\u0300res anne\u0301es, cette the\u0301matique m\u2019a amene\u0301 a\u0300 travailler sur diverses questions. Quand et comment une cellule quitte\u2010t\u2010elle son tissu d\u2019origine ? Comment est contro\u0302le\u0301e la migration directionelle? Quelles influences ont les interactions homotypiques et he\u0301te\u0301rotypiques entre les cellules ? Comment sont inte\u0301gre\u0301s les diffe\u0301rents signaux rec\u0327us de l\u2019environnement local ? Pour tenter de re\u0301pondre a\u0300 ces questions, j\u2019ai utilise\u0301 les cellules de la cre\u0302te neurale, les placodes et le tube neural chez l\u2019embryon de poulet, de Xe\u0301nope et de ze\u0301brafish et des ligne\u0301es cellulaires de cre\u0302tes neurales murines. Par ailleurs, mes projets m\u2019ont amene\u0301 a\u0300 utiliser une grande palette d\u2019outils allant de la biologie mole\u0301culaire, a\u0300 la biochimie en passant par la videomicroscopie, l\u2019optoge\u0301ne\u0301tique, la microfluidique ou encore la culture cellulaire et l\u2019utilisation de biosensors. Enfin, au fil des ans, j\u2019ai de\u0301veloppe\u0301 ou participe\u0301 a\u0300 de nombreuses collaborations avec des physiciens et des mathe\u0301maticiens.<\/p>\n
J\u2019ai essaye\u0301 d\u2019apporter ma contribution a\u0300 la communaute\u0301 par le biais d\u2019organisation de confe\u0301rences internationales permettant la rencontre de la biologie du de\u0301veloppement avec d\u2019autres disciplines. En 2017, nous avons organise\u0301 au Muse\u0301um de Toulouse un meeting du GDR 3604 mode\u0300les aviaires auquel nous avions invite\u0301 des chercheurs travaillant sur le comportement et la ge\u0301nomique. En 2022, nous avons organise\u0301 au CBI un meeting d\u2019optoge\u0301ne\u0301tique au sein duquel de nombreux projets de biologie du de\u0301veloppement e\u0301taient repre\u0301sente\u0301s sur le ze\u0301brafish, la caille ou encore la drosophile, au co\u0302te\u0301 de projets de biologie mole\u0301culaire, de biologie cellulaire, de physiologie, de the\u0301rapie ou encore de comportement. J\u2019ai e\u0301galement participe\u0301 en tant qu\u2019e\u0301diteur invite\u0301 a\u0300 des ouvrages collectifs mettant en avant la biologie du de\u0301veloppement tels que des nume\u0301ros spe\u0301ciaux de Developmental Biology sur l\u2019adhe\u0301rence cellulaire (2015), ou Genesis sur la plasticite\u0301 epithe\u0301lium\u2010me\u0301senchyme (in prep, 2023). Ou encore un livre de la collection Methods in Molecular Biology sur l\u2019EMT (2021) faisant la part belle aux techniques d\u2019investigations des mouvements cellulaires in et ex vivo a\u0300 partir de mode\u0300les embryonnaires.<\/p>\n
En rejoignant la SFBD, j\u2019espe\u0300re apporter ma vision pluridisciplinaire et multi mode\u0300les. La biologie du de\u0301veloppement se de\u0301finie par les questions qu\u2019elle aborde et non par les techniques qu\u2019elle utilise. Je vois donc la biologie du de\u0301veloppement comme un creuset, repre\u0301sentant une opportunite\u0301 unique de casser les barrie\u0300res entre les disciplines. Dans ce contexte, je crois qu\u2019il est important de continuer a\u0300 \u0153uvrer pour un renforcement des liens entre la SFBD et d\u2019autres socie\u0301te\u0301s savantes. Je pense notamment a\u0300 la Socie\u0301te\u0301 de Biologie Cellulaire de France (SBCF), la Socie\u0301te\u0301 Franc\u0327aise de Biologie de la Matrice Extracellulaire (SFBMEc) ou la Socie\u0301te\u0301 Franc\u0327aise du Cancer (SfC) ou encore a\u0300 The Epithelial\u2010Mesenchymal Transition International Association (TEMTIA) dont je suis membre e\u0301lu. Nous devons aussi continuer a\u0300 travailler avec nos colle\u0300gues de\u0301veloppementalistes internationaux dans la tradition de ce qu\u2019a fait la SFBD ces 20 dernie\u0300res anne\u0301es. Mais il nous faut aussi \u0153uvrer a\u0300 cre\u0301er des ponts avec nos colle\u0300gues physiciens, mathe\u0301maticiens, cliniciens, inge\u0301nieurs et informaticiens. Lignage\/identite\u0301, morphogene\u0300se, patterning, he\u0301te\u0301roge\u0301ne\u0301ite\u0301, coope\u0301ration, compe\u0301tition, plasticite\u0301, e\u0301volution, les questions fondamentales de la biologie du de\u0301veloppement et les me\u0301canismes associe\u0301s sont si complexes que l\u2019on ne saurait se priver de la richesse des concepts et des me\u0301thodologies de nos colle\u0300gues des autres champs disciplinaires.<\/p>\n<\/div>\n<\/div>\n<\/div>\n
<\/p>\n
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Stefano TIOZZO, DR CNRS, LBD (Villefranche sur Mer)<\/strong><\/span><\/p>\n![\"\"](\"https:\/\/sfbd.fr\/wp-content\/uploads\/2022\/11\/stefano_photo.jpg\")
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My name is Stefano Tiozzo, I am CNRS-DR2 at the Villefranche sur Mer Developmental Biology Laboratory (LBDV \u2013 UMR7009), and I am writing to propose my candidature for the Board of Direction of the French Society for Developmental Biology.<\/p>\n
I started my scientific career at the CRIBI Biotechnology Center (University of Padova, Italy), comparing the effects of cytokines on muscle regeneration in mouse, rats and chicken using in vitro approaches. Then, at the Smithsonian Tropical Research Institute (Panama), I became interested in marine invertebrates, looking at protein evolution in sea urchins. During the Ph.D., I started focusing on the evolution of nervous systems in the solitary and colonial ascidian, juggling across the University of Padova, the Institut Alfred Fessard (Gif-sur-Yvette) and the University of Queensland (Australia). I got fascinated by the diversity and the plasticity of developmental pathways that characterize this group of chordates. Therefore, during my post-doctoral work at Stanford University (USA), at the Marine Biological Laboratory (USA) and at the UC Santa Barbara (USA), I continued working on different aspects of asexual development and regeneration of colonial tunicates. Rather than focusing on specific mechanistic aspects of development, I became progressively interested on how different developmental pathways can lead to the construction of similar structures, exploring the degrees of freedom and constraints that evolution foist to developmental processes. For this reason, when I joined the CNRS in 2010 leading my own research group at the Villefranche-sur-mer Developmental Biology Laboratory, I mainly keep using tunicates to compare whole-body regeneration and asexual development and to infer their evolution.<\/p>\n
Since I\u2019ve been exposed to a variety of academic and cultural environments, I believe that my international experience and my interests on \u201cless characteristic\u201d aspects of development, could bring different new perspectives and be of service for the SFBD. If elected, I would particularly like to enforce the outreach aspects of the Society. Particularly proposing means to share with non-scientific audience the basis of evolution and development as driving forces of life form diversity. I believe that, at this historical stage, the scientific popularization of these concepts and the promotion of scientific critical thinking is becoming for us more and more a duty.<\/p>\n<\/div>\n<\/div>\n<\/div>\n
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Laurent YVERNOGEAU, CR INSERM, IBPS (Paris)<\/strong><\/span><\/p>\n![\"\"](\"https:\/\/sfbd.fr\/wp-content\/uploads\/2022\/11\/laurent.jpg\")
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J\u2019ai r\u00e9alis\u00e9 ma th\u00e8se en biologie du d\u00e9veloppement \u00e0 l\u2019universit\u00e9 de Nantes en 2009 sous la direction de Josiane Fontaine-P\u00e9rus. Ma th\u00e8se portait sur les origines ainsi que les interactions entre les cellules endoth\u00e9liales et les cellules musculaires qui colonisent le membre de l\u2019embryon.<\/p>\n
J\u2019ai poursuivi par un premier Post-doctorat \u00e0 Paris (2010-2012), dans le laboratoire de Thierry Jaffredo, o\u00f9 je me suis attach\u00e9 \u00e0 d\u00e9velopper un syst\u00e8me de culture cellulaire permettant de r\u00e9capituler les \u00e9tapes pr\u00e9coces de formations de cellules h\u00e9matopo\u00ef\u00e9tiques \u00e0 partir de cellules endoth\u00e9liales issues du m\u00e9soderme pr\u00e9somitique. J\u2019ai \u00e9galement utilis\u00e9 le syst\u00e8me de greffes chim\u00e8res caille\/poulet et poulet GFP\/poulet pour \u00e9tudier le d\u00e9veloppement de la vascularisation de la moelle osseuse.<\/p>\n
J\u2019ai ensuite effectu\u00e9 un second Post-doctorat \u00e0 Utrecht aux Pays-Bas \u00e0 l\u2019Institut Hubrecht dans le laboratoire de Catherine Robin (2013-2020). J\u2019y ai poursuivi mes \u00e9tudes sur le d\u00e9veloppement du syst\u00e8me h\u00e9matopo\u00ef\u00e9tique chez l\u2019embryon et utilis\u00e9 des techniques de transcriptomiques spatiales (Tomo-seq).<\/p>\n
Je suis rentr\u00e9 en France au d\u00e9but de l\u2019ann\u00e9e 2021 et obtenu un poste de CRCN \u00e0 l\u2019INSERM en 2022 pour d\u00e9chiffrer les \u00e9tapes pr\u00e9coces de formation de cellules endoth\u00e9liales h\u00e9mog\u00e9niques en utilisant des approches de greffes h\u00e9t\u00e9rosp\u00e9cifiques (caille-poule) sur l\u2019embryon d\u2019oiseau, des approches de culture cellulaire in vitro<\/em> (lign\u00e9es primaires et huiPSCs) et des approches de transcriptomiques (scRNA-seq, transcriptomique spatiale).<\/p>\nJe suis membre de la SFBD depuis plusieurs ann\u00e9es et depuis mon retour des Pays-Bas, je souhaiterai devenir un membre actif de la SFBD. C\u2019est notamment au travers des congr\u00e8s de la SFBD que j\u2019ai eu la chance de pouvoir pr\u00e9senter mes premiers travaux de recherche, une premi\u00e8re \u00e9tape importante dans la vie d\u2019un chercheur. C\u2019est mon int\u00e9r\u00eat pour la biologie du d\u00e9veloppement qui me suit depuis le d\u00e9but de ma carri\u00e8re qui m\u2019entra\u00eene naturellement \u00e0 proposer ma candidature en postulant au CA de la SFBD. M\u2019investir au sein de la SFBD sera pour moi un moyen de transmettre ma passion aux jeunes chercheurs mais aussi d\u2019essayer de d\u00e9velopper et de maintenir l\u2019int\u00e9r\u00eat de cette discipline au sein de la communaut\u00e9 scientifique. Pour cette raison j\u2019aimerai investir pleinement au sein de la SFBD pour promouvoir la mobilit\u00e9 des jeunes chercheurs \u00e0 travers l\u2019obtention de prix scientifiques ou de bourses de voyage pour pr\u00e9senter leurs travaux de recherche et pour d\u00e9velopper leur r\u00e9seau professionnel.<\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"
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