{"id":4231,"date":"2019-06-27T19:26:52","date_gmt":"2019-06-27T17:26:52","guid":{"rendered":"https:\/\/sfbd.fr\/2019\/06\/27\/en-2019-le-prix-de-these-sfbd-a-ete-attribue-a-meryem-baghdadi\/"},"modified":"2020-06-24T23:55:14","modified_gmt":"2020-06-24T21:55:14","slug":"en-2019-le-prix-de-these-sfbd-a-ete-attribue-a-meryem-baghdadi","status":"publish","type":"post","link":"https:\/\/sfbd.fr\/en\/2019\/06\/27\/en-2019-le-prix-de-these-sfbd-a-ete-attribue-a-meryem-baghdadi\/","title":{"rendered":"Thesis Prize SFBD 2019: Dr. Meryem Baghdadi"},"content":{"rendered":"<p>[vc_row][vc_column][vc_column_text]<\/p>\r\n<h5><strong>First prize :<\/strong><br><strong>\u2192 Invitation to give a plenary talk during the EDBC meeting in Alicante, 23 &#8211; 26 October, 2019<\/strong><\/h5>\r\n<h5><strong>\u2192 Prize of 1000 \u20ac<\/strong><\/h5>\r\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2740 size-medium alignleft\" src=\"https:\/\/sfbd.fr\/wp-content\/uploads\/2019\/06\/MBB-COL-fibre-300x216.jpg\" alt=\"\" width=\"300\" height=\"216\" srcset=\"https:\/\/sfbd.fr\/wp-content\/uploads\/2019\/06\/MBB-COL-fibre-300x216.jpg 300w, https:\/\/sfbd.fr\/wp-content\/uploads\/2019\/06\/MBB-COL-fibre-768x554.jpg 768w, https:\/\/sfbd.fr\/wp-content\/uploads\/2019\/06\/MBB-COL-fibre.jpg 1024w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>In 2019, the SFBD thesis prize was awarded to Dr. Meryem Baghdadi for her doctorate entitled: \u00ab Regulation of adult muscle stem cell quiescence by Notch signaling \u00bb. Her work has been published in <a href=\"https:\/\/www.nature.com\/articles\/s41586-018-0144-9\" target=\"_blank\" rel=\"noopener noreferrer\">Nature<\/a> and <a href=\"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1934-5909(18)30481-8\" target=\"_blank\" rel=\"noopener noreferrer\">Cell Stem Cell<\/a>. <span tabindex=\"0\" lang=\"en\">Meryem Baghdadi did her thesis under the supervision of <\/span>&nbsp;Pr. Shahragim Tajbakhsh et Dr. Philippos Mourikis, in the laboratory <a href=\"https:\/\/research.pasteur.fr\/fr\/team\/stem-cells-and-development\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u00ab <\/a><a href=\"https:\/\/research.pasteur.fr\/fr\/team\/stem-cells-and-development\/\" target=\"_blank\" rel=\"noopener noreferrer\">Stem cells and development \u00bb<\/a> at the Pasteur Institute, in Paris.&nbsp;<\/p>\r\n\r\n<h4 class=\"wp-block-heading\"><a href=\"https:\/\/sfbd.fr\/wp-content\/uploads\/2019\/06\/graphicalabstract.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-2738\" src=\"https:\/\/sfbd.fr\/wp-content\/uploads\/2019\/06\/graphicalabstract.jpg\" alt=\"\" width=\"500\" height=\"163\" srcset=\"https:\/\/sfbd.fr\/wp-content\/uploads\/2019\/06\/graphicalabstract.jpg 1904w, https:\/\/sfbd.fr\/wp-content\/uploads\/2019\/06\/graphicalabstract-300x98.jpg 300w, https:\/\/sfbd.fr\/wp-content\/uploads\/2019\/06\/graphicalabstract-768x250.jpg 768w, https:\/\/sfbd.fr\/wp-content\/uploads\/2019\/06\/graphicalabstract-1024x334.jpg 1024w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/a><\/h4>\r\n<p>&nbsp;<\/p>\r\n<h4><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2726 size-full alignright\" src=\"https:\/\/sfbd.fr\/wp-content\/uploads\/2019\/06\/Meryem-Baghdadi.jpg\" alt=\"\" width=\"205\" height=\"283\"><\/h4>\r\n<h4>About the winner :<\/h4>\r\n<p><span tabindex=\"0\" lang=\"en\">The thesis work of Meryem Baghdadi revealed two spectacular new modes of action for the Notch signaling pathway to maintain the quiescence of muscle stem cells in the adult niche. On the one hand Notch acts by stimulating the synthesis of Collagen V, which is a major molecule of the extracellular matrix of the niche; on the other hand Notch induces the expression of a specific microRNA which acts by inhibiting the expression of genes necessary for migration, thus preventing the exit and differentiation of stem cells out of the niche.<\/span><\/p>\r\n\r\n<a href=\"http:\/\/www.theses.fr\/en\/2017PA066461#\" target=\"_blank\" class=\"fw-btn fw-btn-1 fw-btn-black\">\n\t<span>Link to the thesis summary<\/span>\n<\/a>\r\n\r\n<p>&nbsp;<\/p>\r\n\r\n<h4>&nbsp;<\/h4>\r\n<p>&nbsp;<\/p>\r\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>","protected":false},"excerpt":{"rendered":"<p>For her doctorate entitled: \u00ab Regulation of adult muscle stem cell quiescence by Notch signaling \u00bb<\/p>\n","protected":false},"author":1,"featured_media":3079,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.2 - 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