![\"\"](\"https:\/\/sfbd.fr\/wp-content\/uploads\/2019\/12\/Florence-Giger_cropped-217x300.jpg\")
<\/strong>European Developmental Biology Congress<\/strong>\n<\/strong><\/h4>\n
\u2192 400 \u20ac Prize<\/strong><\/h5>\nPostdoc with Corinne Houart, King\u2019s College, London<\/i><\/strong><\/em><\/strong><\/p>\n– article in French<\/em> –<\/p>\nLe congr\u00e8s a r\u00e9uni dans l\u2019auditorium de la Disputacio d\u2019Alicante 600 participants provenant majoritairement mais pas exclusivement de laboratoires europ\u00e9ens, autour de th\u00e8mes illustrant la diversit\u00e9 de la biologie du d\u00e9veloppement \u00e0 l\u2019heure actuelle, de l\u2019organisation 4D du g\u00e9nome aux ph\u00e9nom\u00e8nes biom\u00e9caniques sous-tendant les m\u00e9canismes morphog\u00e9n\u00e9tiques. Ce type de congr\u00e8s permet d\u2019avoir un excellent aper\u00e7u des th\u00e9matiques actuellement abord\u00e9es dans tous les domaines de biologie du d\u00e9veloppement, et des techniques utilis\u00e9es et d\u00e9velopp\u00e9es pour r\u00e9pondre aux questions pos\u00e9es actuellement. Denis Duboule (Suisse) a ainsi pr\u00e9sent\u00e9 les avantages et limitations des organo\u00efdes pour \u00e9tudier l\u2019architecture et l\u2019organisation du g\u00e9nome.<\/p>\n
La session d\u2019ouverture a donn\u00e9 le ton avec une excellente double pr\u00e9sentation de Nipam Patel (Massachussetts, Etats-Unis), aussi fascinant sur la strat\u00e9gie \u00e9volutive de type couteau-suisse des crustac\u00e9es que sur la diversit\u00e9 de coloration des ailes de papillon. Les organismes non conventionnels \u00e9taient \u00e0 l\u2019honneur, Eve Sauntjens (Belgique) nous a ainsi fait d\u00e9couvrir la richesse de l\u2019embryon d\u2019octopus qui, bien que faisant partie du clade des mollusques, pr\u00e9sente de nombreuses similarit\u00e9s avec les mammif\u00e8res au niveau de l\u2019organisation du syst\u00e8me nerveux, nourrissant la th\u00e9orie de la convergence \u00e9volutive. Enfin, j\u2019ai \u00e9t\u00e9 fascin\u00e9e par les travaux de Nicolas Rohner (Kansas, Etats-Unis), identifiant un ensemble de particularit\u00e9s de type diab\u00e8te chez les cavefish, ce qui leur permet d\u2019augmenter naturellement leur prise de poids suite \u00e0 l\u2019inondation annuelle de leur caverne leur apportant leur nourriture. Ces caract\u00e9ristiques de type diab\u00e8te s\u2019accompagnent d\u2019un syst\u00e8me immunitaire relativement faible qui leur permet de ne pas souffrir d\u2019inflammation et n\u2019est pas d\u00e9l\u00e9t\u00e8re dans un environnement a faible charge parasitique.<\/p>\n
En lien plus direct avec mon \u00e9tude des m\u00e9canismes de neurulation dans le cerveau ant\u00e9rieur, les pr\u00e9sentations li\u00e9es \u00e0 la morphogen\u00e8se ont \u00e9t\u00e9 particuli\u00e8rement int\u00e9ressantes. Ainsi, Roberto Mayor (Royaume Uni) a pr\u00e9sent\u00e9 un mod\u00e8le de migration collective des cr\u00eates neurales, mettant en \u00e9vidence l\u2019importance de l\u2019anisotropie de contractilit\u00e9 au sein d\u2019un groupe de cellules pour promouvoir leur migration collective. Luis Maria Escudero (Espagne) a d\u00e9crit le principe biophysique des scutoides, une transition T1 spatiale apico-basale, qui permet de lier connexion cellulaire et courbure d\u2019un tissu, ce qui est crucial au cours de la morphogen\u00e8se d\u2019un \u00e9pith\u00e9lium. Ces scutoides ayant \u00e9t\u00e9 observ\u00e9s dans de nombreux \u00e9pith\u00e9liums, il est probable qu\u2019ils jouent \u00e9galement un r\u00f4le au cours de la neurulation de la plaque neural ant\u00e9rieure.<\/p>\n
Les sessions posters ont permis de nombreuses interactions scientifiques et techniques. J\u2019ai en particulier pu discuter de nouvelles techniques d\u2019analyse de donn\u00e9es 4d acquises par microscopie confocale lightsheet et d\u2019\u00e9changer de mani\u00e8re tr\u00e8s concr\u00e8te sur l\u2019utilisation d\u2019un logiciel d\u2019analyse d\u2019images qui vient d\u2019\u00eatre acquis par notre d\u00e9partement. Les discussions autour de mon poster m\u2019ont permis d\u2019identifier les points les plus int\u00e9ressants aux yeux de la communaut\u00e9 et les questions sur lesquelles me pencher en priorit\u00e9.<\/p>\n
Enfin, les pauses caf\u00e9, d\u00e9jeuner et diner ont permis d\u2019\u00e9tablir de nouveaux contacts au sein de la communaut\u00e9 europ\u00e9enne de biologie du d\u00e9veloppement, autour de conversations scientifiques informelles aussi sympathiques qu\u2019int\u00e9ressantes![\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"
European Developmental Biology Congress<\/p>\n","protected":false},"author":6,"featured_media":4360,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[90],"tags":[],"yoast_head":"\n
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– article in French<\/em> –<\/p>\n Le congr\u00e8s a r\u00e9uni dans l\u2019auditorium de la Disputacio d\u2019Alicante 600 participants provenant majoritairement mais pas exclusivement de laboratoires europ\u00e9ens, autour de th\u00e8mes illustrant la diversit\u00e9 de la biologie du d\u00e9veloppement \u00e0 l\u2019heure actuelle, de l\u2019organisation 4D du g\u00e9nome aux ph\u00e9nom\u00e8nes biom\u00e9caniques sous-tendant les m\u00e9canismes morphog\u00e9n\u00e9tiques. Ce type de congr\u00e8s permet d\u2019avoir un excellent aper\u00e7u des th\u00e9matiques actuellement abord\u00e9es dans tous les domaines de biologie du d\u00e9veloppement, et des techniques utilis\u00e9es et d\u00e9velopp\u00e9es pour r\u00e9pondre aux questions pos\u00e9es actuellement. Denis Duboule (Suisse) a ainsi pr\u00e9sent\u00e9 les avantages et limitations des organo\u00efdes pour \u00e9tudier l\u2019architecture et l\u2019organisation du g\u00e9nome.<\/p>\n La session d\u2019ouverture a donn\u00e9 le ton avec une excellente double pr\u00e9sentation de Nipam Patel (Massachussetts, Etats-Unis), aussi fascinant sur la strat\u00e9gie \u00e9volutive de type couteau-suisse des crustac\u00e9es que sur la diversit\u00e9 de coloration des ailes de papillon. Les organismes non conventionnels \u00e9taient \u00e0 l\u2019honneur, Eve Sauntjens (Belgique) nous a ainsi fait d\u00e9couvrir la richesse de l\u2019embryon d\u2019octopus qui, bien que faisant partie du clade des mollusques, pr\u00e9sente de nombreuses similarit\u00e9s avec les mammif\u00e8res au niveau de l\u2019organisation du syst\u00e8me nerveux, nourrissant la th\u00e9orie de la convergence \u00e9volutive. Enfin, j\u2019ai \u00e9t\u00e9 fascin\u00e9e par les travaux de Nicolas Rohner (Kansas, Etats-Unis), identifiant un ensemble de particularit\u00e9s de type diab\u00e8te chez les cavefish, ce qui leur permet d\u2019augmenter naturellement leur prise de poids suite \u00e0 l\u2019inondation annuelle de leur caverne leur apportant leur nourriture. Ces caract\u00e9ristiques de type diab\u00e8te s\u2019accompagnent d\u2019un syst\u00e8me immunitaire relativement faible qui leur permet de ne pas souffrir d\u2019inflammation et n\u2019est pas d\u00e9l\u00e9t\u00e8re dans un environnement a faible charge parasitique.<\/p>\n En lien plus direct avec mon \u00e9tude des m\u00e9canismes de neurulation dans le cerveau ant\u00e9rieur, les pr\u00e9sentations li\u00e9es \u00e0 la morphogen\u00e8se ont \u00e9t\u00e9 particuli\u00e8rement int\u00e9ressantes. Ainsi, Roberto Mayor (Royaume Uni) a pr\u00e9sent\u00e9 un mod\u00e8le de migration collective des cr\u00eates neurales, mettant en \u00e9vidence l\u2019importance de l\u2019anisotropie de contractilit\u00e9 au sein d\u2019un groupe de cellules pour promouvoir leur migration collective. Luis Maria Escudero (Espagne) a d\u00e9crit le principe biophysique des scutoides, une transition T1 spatiale apico-basale, qui permet de lier connexion cellulaire et courbure d\u2019un tissu, ce qui est crucial au cours de la morphogen\u00e8se d\u2019un \u00e9pith\u00e9lium. Ces scutoides ayant \u00e9t\u00e9 observ\u00e9s dans de nombreux \u00e9pith\u00e9liums, il est probable qu\u2019ils jouent \u00e9galement un r\u00f4le au cours de la neurulation de la plaque neural ant\u00e9rieure.<\/p>\n Les sessions posters ont permis de nombreuses interactions scientifiques et techniques. J\u2019ai en particulier pu discuter de nouvelles techniques d\u2019analyse de donn\u00e9es 4d acquises par microscopie confocale lightsheet et d\u2019\u00e9changer de mani\u00e8re tr\u00e8s concr\u00e8te sur l\u2019utilisation d\u2019un logiciel d\u2019analyse d\u2019images qui vient d\u2019\u00eatre acquis par notre d\u00e9partement. Les discussions autour de mon poster m\u2019ont permis d\u2019identifier les points les plus int\u00e9ressants aux yeux de la communaut\u00e9 et les questions sur lesquelles me pencher en priorit\u00e9.<\/p>\n Enfin, les pauses caf\u00e9, d\u00e9jeuner et diner ont permis d\u2019\u00e9tablir de nouveaux contacts au sein de la communaut\u00e9 europ\u00e9enne de biologie du d\u00e9veloppement, autour de conversations scientifiques informelles aussi sympathiques qu\u2019int\u00e9ressantes![\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":" European Developmental Biology Congress<\/p>\n","protected":false},"author":6,"featured_media":4360,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[90],"tags":[],"yoast_head":"\n