{"id":6150,"date":"2020-06-24T13:13:16","date_gmt":"2020-06-24T11:13:16","guid":{"rendered":"https:\/\/sfbd.fr\/?p=6150&#038;preview=true&#038;preview_id=6150"},"modified":"2020-06-25T11:51:47","modified_gmt":"2020-06-25T09:51:47","slug":"finaliste-prix-de-these-sfbd-2020-dr-alicia-lardennois","status":"publish","type":"post","link":"https:\/\/sfbd.fr\/en\/2020\/06\/24\/finaliste-prix-de-these-sfbd-2020-dr-alicia-lardennois\/","title":{"rendered":"Finalist Thesis Prize SFBD 2020: Dr. Alicia Lardennois"},"content":{"rendered":"<p>[vc_row][vc_column][vc_column_text]<\/p>\n<h5>&nbsp;<strong>Finalist :<\/strong><\/h5>\n<h5><strong>\u2192 Prize of 300 \u20ac <\/strong><\/h5>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-6151\" src=\"https:\/\/sfbd.fr\/wp-content\/uploads\/2020\/06\/Capture-d\u2019e\u0301cran-2020-06-24-a\u0300-21.32.19-213x300.png\" alt=\"\" width=\"200\" height=\"282\" srcset=\"https:\/\/sfbd.fr\/wp-content\/uploads\/2020\/06\/Capture-d\u2019e\u0301cran-2020-06-24-a\u0300-21.32.19-213x300.png 213w, https:\/\/sfbd.fr\/wp-content\/uploads\/2020\/06\/Capture-d\u2019e\u0301cran-2020-06-24-a\u0300-21.32.19.png 391w\" sizes=\"(max-width: 200px) 100vw, 200px\" \/>In 2020, the SFBD selected Dr. Alicia Lardennois as a co-finalist for the thesis prize for her thesis entitled: &#8220;Contribution of actin cytoskeleton to C. elegans embryonic elongation&#8221;. This work was published in the journal <a href=\"https:\/\/www.nature.com\/articles\/s41586-019-1509-4\" target=\"_blank\" rel=\"noopener noreferrer\">Nature<\/a> in 2019.<\/p>\n<p>Alicia Lardennois did her thesis under the supervision of Dr. Michel Labouesse at the <a href=\"https:\/\/www.ibps.upmc.fr\/en\" target=\"_blank\" rel=\"noopener noreferrer\">Institut de Biologie Paris Seine<\/a> in Paris.<\/p>\n<p>&nbsp;<\/p>\n\n<h5 class=\"wp-block-heading\">The work of the winner :<\/h5>\n\n<div>\n<h4><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-6153 size-full alignright\" src=\"https:\/\/sfbd.fr\/wp-content\/uploads\/2020\/06\/LARDENNOIS_Alicia_Photo.jpg\" alt=\"\" width=\"200\" height=\"200\"><\/h4>\n<p>Alicia Lardennois&#8217; thesis work focused on the characterization of the mechanical forces acting during embryonic elongation of the nematode <em>C. elegans<\/em>. This organism elongates without rearrangement or cell division, solely through changes in the shape of epidermal cells. This elongation depends on muscle activity. The results of Alicia Lardennois&#8217; thesis work have led to the identification of a new cellular network that acts by progressively remodelling the actin cytoskeleton and stabilising cell shapes in a ratchet-like process, which provides the plasticity necessary for the elongation of the embryo in response to muscle contractions. These results were obtained using a multidisciplinary approach ranging from the molecular genetics of <em>C. elegans<\/em> to super-resolution imaging and the design of a mesoscopic model of the embryo.<\/p>\n<\/div>\n<div>&nbsp;<\/div>\n<a href=\"http:\/\/www.theses.fr\/2019SORUS236\" target=\"_blank\" class=\"fw-btn fw-btn-1 fw-btn-black\">\n\t<span>Link to the thesis summary<\/span>\n<\/a>\n<p><br>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><!-- \/wp:paragraph --><br><!-- wp:paragraph --><!-- \/wp:paragraph -->&nbsp;<\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pour sa th\u00e8se intitul\u00e9e:\u00a0 \u201cContribution of actin cytoskeleton to C. elegans embryonic elongation\u201d<\/p>\n","protected":false},"author":7,"featured_media":6155,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.2 - 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