Article in French<\/em> –<\/p>\nEnfin ! Malgr\u00e9 quelques d\u00e9sagr\u00e9ments prenant la forme d\u2019une pand\u00e9mie mondiale et plusieurs mois de confinement for\u00e7ant le d\u00e9calage d\u2019un an de la conf\u00e9rence et le d\u00e9placement g\u00e9ographique des calanques \u00e0 nos bureaux, Shaping life 2 a eu lieu ! Trois jours \u00e0 \u00e9cumer les diverses facettes de la biologie du d\u00e9veloppement, de la m\u00e9canobiologie \u00e0 la toxicologie, ce fut un panorama stimulant des recherches actuelles. De plus, malgr\u00e9 la d\u00e9sormais tristement c\u00e9l\u00e8bre distanciation sociale, l\u2019organisation sous forme de hall virtuel, permettant \u00e0 nos avatars de se d\u00e9placer de stand en poster et de discuter \u00e0 la vol\u00e9e avec les autres participants, a permis d\u2019\u00e9voquer le bouillonnement intellectuel et humain de ce genre de conf\u00e9rences. Il ne manquait que l\u2019odeur du caf\u00e9 pour s\u2019y croire.<\/p>\n
La le\u00e7on inaugurale par Alphonso Martinez Arias fut, comme \u00e0 l\u2019accoutum\u00e9e, stimulante, brossant le portrait de la biologie du d\u00e9veloppement aujourd\u2019hui et tra\u00e7ant dans les grandes lignes les directions futures de la discipline. Quelle meilleure entr\u00e9e en mati\u00e8re pour une conf\u00e9rence couvrant un domaine si vaste\u00a0?<\/p>\n
Je ne pourrai faire honneur \u00e0 toutes les pr\u00e9sentations dans un si petit r\u00e9sum\u00e9, je me contenterai donc de celles qui m\u2019ont le plus marqu\u00e9. Avant m\u00eame cette le\u00e7on inaugurale ont eu lieu des discussions sur le financement et la publication des travaux scientifiques qui apporte aux jeunes chercheurs un \u00e9clairage sur les conditions dans lesquelles ils vont travailler, ce qui n\u2019est pas \u00e0 n\u00e9gliger lorsque l\u2019on se consacre \u00e0 la recherche.<\/p>\n
Nous avons beaucoup entendu parler d\u2019organo\u00efdes, de gastrulo\u00efdes, ces outils si pratiques et puissants pour \u00e9tudier des ph\u00e9nom\u00e8nes autrement inaccessibles ou pour perturber des syst\u00e8mes de mani\u00e8re nouvelle afin d\u2019en observer les r\u00e9actions et comprendre leur fonctionnement. J\u2019ai particuli\u00e8rement appr\u00e9ci\u00e9 la conf\u00e9rence de Jorge Torres-Paz, qui a recours \u00e0 la fabrication de pesco\u00efdes pour \u00e9tudier le lien entre morphog\u00e9n\u00e8se et g\u00e9n\u00e9tique dans deux populations en cours de sp\u00e9ciation du poisson Astyanax mexicanus. Effray\u00e9 par aucun n\u00e9ologisme, Jorge nous a pr\u00e9sent\u00e9 ses surfo\u00efdes et des caveo\u00efdes, d\u00e9riv\u00e9s des formes sauvages et cavernicoles de ce poisson, qui ont fait de l\u2019\u0153il aux sp\u00e9cialistes de la formation de la r\u00e9tine.<\/p>\n
Une intervention impressionnante a \u00e9t\u00e9 donn\u00e9e par Stefan Preibisch sur comment manipuler les \u00e9normes quantit\u00e9s de donn\u00e9es que l\u2019on peut d\u00e9sormais acqu\u00e9rir \u00e0 l\u2019aide de la microcopie en nappe de lumi\u00e8re. En effet, il ne faut pas laisser le d\u00e9veloppement technologique de c\u00f4t\u00e9 lorsque l\u2019on \u00e9tudie le d\u00e9veloppement embryonnaire et filmer un embryon n\u2019est pas tout, il faut pouvoir l\u2019analyser, diss\u00e9quer le film et en extraire les informations qui ont du sens.<\/p>\n
Sur un tout autre sujet, la conf\u00e9rence de Thibaut Brunet sur la possible \u00e9mergence de la multicellularit\u00e9 chez les choanoflagell\u00e9es a retenu mon attention. En effet, habitu\u00e9s que nous sommes \u00e0 observer l\u2019assemblage et la complexification d\u2019un embryon, nous en venons \u00e0 oublier qu\u2019\u00e0 l\u2019origine, les cellules vivaient seule leur vie, que la multicellularit\u00e9 a vraisemblablement \u00e9merg\u00e9 \u00e0 plusieurs reprises et que les m\u00e9canismes conduisant \u00e0 la coop\u00e9ration de protistes sont encore mal connus.<\/p>\n
Finalement, la derni\u00e8re conf\u00e9rence, par Cassandra Extavour sur comment les contraintes d\u00e9veloppementales impos\u00e9es par la forme et la taille d\u2019un \u0153uf influencent le d\u00e9veloppement fut le clou du spectacle. Elle a apport\u00e9, du moins pour moi, une lumi\u00e8re nouvelle sur les restrictions qui p\u00e8sent sur l\u2019embryon, l\u2019emp\u00eachant de prendre n\u2019importe quelle forme ou taille.<\/p>\n
Ainsi, Shaping Life 2 fut pour moi une exp\u00e9rience excitante, j\u2019ai pu y faire quelques rencontres ainsi que croiser des connaissances, sans avoir \u00e0 passer par le laborieux et formel contact par mail apr\u00e8s un talk, qui est le lot des conf\u00e9rences \u00e0 distance.<\/p>\n
La conf\u00e9rence tiens sa promesse, de rassembler un large panel de sp\u00e9cialit\u00e9s li\u00e9es au d\u00e9veloppement, donnant ainsi un instantan\u00e9 de la pratique de cette vaste communaut\u00e9. Il ne manquait que l\u2019odeur piquante du sel et celle, plus am\u00e8re, du pastis.<\/strong><\/p>\n\u2192\u00a0<\/strong>Arthur Boutillon presented a poster entitled: “Mechanical control of axial mesoderm migration during Zebrafish gastrulation”<\/p>\n![\"\"](\"https:\/\/sfbd.fr\/wp-content\/uploads\/2021\/04\/Illustration_AB.jpg\")
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Shaping Life 2<\/p>\n","protected":false},"author":6,"featured_media":7868,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[90],"tags":[],"yoast_head":"\n
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